Sas-6 mutant flies are uncoordinated, and this phenotype is rescued by the expression of Sas-6-GFP. This montage shows short video clips of flies of the following genotypes: WT; Sas-6 mutant ( Sas-6−/−); Sas-6 mutant rescued by Sas-6-GFP flies (Sas-6-GFP; Sas-6−/−). Like all flies that lack centrioles, the Sas-6 mutant is strongly uncoordinated because of the lack of cilia in its sensory neurons ( Basto et al., 2006); this uncoordinated phenotype is strongly rescued by the expression of Sas-6-GFP. See also Fig. S1 C.
