Video 7.

Dsp deletion results in enhanced keratinocyte collective migration. Representative phase-contrast time-lapse videos of Dsp+/+ (left) and Dsp−/− (right) keratinocytes migrating on type I collagen (corresponds with Fig. 4 H). Dsp−/− cells (right) migrated at an enhanced rate compared with Dsp+/+ cells (left). Cells were imaged every 10 min for 16 h using an AxioObserver Z1 microscope equipped with an EC Plan Neofluar 10×/0.3 Ph1 objective. Timestamp is displayed in the hh:mm:ss format. Bar, 200 µm.


Keratin 6 regulates collective keratinocyte migration by altering cell–cell and cell–matrix adhesion

Fengrong Wang, Song Chen, Hans B. Liu, Carole A. Parent, and Pierre A. Coulombe

DOI: 10.1083/jcb.201712130
Download Original Video
powered by Glencoe Software