Output of a random walk simulation. Left: Upper panel shows the positions of a theoretical GPCR after each time step on an unwrapped and flattened cilium membrane surface; lower panel shows the position of the theoretical GPCR (red dot) on the 3D cylindrical membrane. Right: Axial position of the theoretical GPCR as a function of time (axial kymograph), where the position has been blurred by a Gaussian kernel, with σ = σ x,y of the psf, to simulate the blurring of the Qdot by the optical system. Parameters of the simulation: lcyl = 5 µm, Dm = 0.15 µm2/s, ts = 0.3 s. Video recorded at 24 fps, accelerated fivefold.
