Video 8.

Time-lapse confocal microscopy of JHU12 cells (red) migrating on NF-derived CDM (green) or CAF-derived CDM (green). (Left) NF-derived CDM. (Right) CAF-derived CDM. Note the nondirectional cancer cell migration around the NF CDM and the directional cell migration along CAF CDM fibers. Images were taken every 7.5 min for 3 h. Display rate, 7 fps. Bar, 20 µm. Still images are shown in Fig. S2 E.


Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin

Begum Erdogan, Mingfang Ao, Lauren M. White, Anna L. Means, Bryson M. Brewer, Lijie Yang, M. Kay Washington, Chanjuan Shi, Omar E. Franco, Alissa M. Weaver, Simon W. Hayward, Deyu Li, and Donna J. Webb

DOI: 10.1083/jcb.201704053
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