Time-lapse confocal microscopy of co-culture migration of DU145 prostate cancer cells (red) with CAFs (green). Three individual fields are shown. Note that the DU145 cancer cell moves toward and along the CAF in a directionally persistent manner. Images were taken every 10 min for 6 h. Display rate, 4 fps. Bar, 20 µm. Still images are shown in Fig. 1 A.
