Video 4.

GIT1 oscillates between invadopodia core and the ring. EGFP-GIT1 was expressed in MTLn3 cells, cotransfected with an invadopodia marker cortactin-mTagRFP, and imaged every minute for 1 h. Widefield microscopy imaging was used, followed by image deconvolution.


Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

Sara K. Donnelly, Ramon Cabrera, Serena P.H. Mao, John R. Christin, Bin Wu, Wenjun Guo, Jose Javier Bravo-Cordero, John S. Condeelis, Jeffrey E. Segall, and Louis Hodgson

DOI: 10.1083/jcb.201704048
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