Video 4.

Myosin dynamics in NBs ingressing as clusters of cells in a Delta-RNAi embryo. Time-lapse video of a Delta-RNAi embryo showing a cluster of ingressing NBs (encircled in white in the first time frame). Myosin is labeled in green (Sqh::GFP), and the cell membranes are labeled in red (GAP43::mCherry). Notice that myosin accumulates in persistent puncta as multiple cells attempt to ingress together. After a “tug of war” between cells, their apically constricted membranes snap back and disrupt collective ingression. Video is displayed at 20 frames per second.


Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression

Sérgio Simões, Youjin Oh, Michael F.Z. Wang, Rodrigo Fernandez-Gonzalez, and Ulrich Tepass

DOI: 10.1083/jcb.201608038
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