Video 1.

Chromosome dynamics and mitotic progression in control U2OS cells. Mitotic cells efficiently align chromosomes and enter anaphase. U2OS histone H2A.Z-mCherry cells after control RNAi were imaged at 1-min intervals and are displayed at eight frames per second.

GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK

Shweta Bendre, Arnaud Rondelet, Conrad Hall, Nadine Schmidt, Yu-Chih Lin, Gary J. Brouhard, and Alexander W. Bird

DOI: 10.1083/jcb.201606081