Video 4.

Time-lapse DIC video of ZYG11A/B siRNA plus proTAME-treated U2OS cells. The DIC video covers 15 h at 3-min intervals; the time counter is in the top right corner.

The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage

Riju S. Balachandran, Cassandra S. Heighington, Natalia G. Starostina, James W. Anderson, David L. Owen, Srividya Vasudevan, and Edward T. Kipreos

DOI: 10.1083/jcb.201601083