Video 9.

Cdc42 and β-PIX are required for the P-cadherin–dependent increase in intercellular stresses. Monolayer stress component σ xx of migrating C2C12 Pcad Cdc42 shRNA (left) and C2C12 Pcad β-PIX shRNA (right) cells; 1 frame/30 min for 10 h.

P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forces

Cédric Plutoni, Elsa Bazellieres, Maïlys Le Borgne-Rochet, Franck Comunale, Agusti Brugues, Martial Séveno, Damien Planchon, Sylvie Thuault, Nathalie Morin, Stéphane Bodin, Xavier Trepat, and Cécile Gauthier-Rouvière

DOI: 10.1083/jcb.201505105