Video 7.

Fzy localizes on laser-induced DNA breaks. WT neuroblast expressing GFP::Fzy (left, cyan on right) and H2A.Z::RFP (red) before and after laser-induced DNA breaks. The yellow circle indicates the site of laser ablation. The arrows indicate the appearance of GFP::Fzy signal on the breaks. Images were analyzed by a time-lapse confocal spinning disk microscope equipped with an Evolve emCCD camera. Frames were taken every 20 s. Time is given in minutes/seconds. The video corresponds to Fig. 4 B (top).


Bub3–BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomes

Nicolas Derive, Cedric Landmann, Emilie Montembault, Marie-Charlotte Claverie, Priscillia Pierre-Elies, Damien Goutte-Gattat, Nabila Founounou, Derek McCusker, and Anne Royou

DOI: 10.1083/jcb.201504059
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