Video 4.

Movie of Plk4^AID/AID;p53 shRNA cell treated for 2 wk with IAA and coexpressing TagRFP-tubulin (red), EGFP-Histone H2B (green), and EGFP-Cep63 (green). Images were analyzed by time-lapse confocal microscopy using a laser-scanning confocal microscope. Shown in Fig. 5 E (Chronic IAA). One frame captured every 3 min; displayed at 10 frames/s.

p53 protects against genome instability following centriole duplication failure

Bramwell G. Lambrus, Yumi Uetake, Kevin M. Clutario, Vikas Daggubati, Michael Snyder, Greenfield Sluder, and Andrew J. Holland

DOI: 10.1083/jcb.201502089