Video 2.

Septin knockdown impedes FA maturation. MDCK-paxillin-GFP cells were transfected with control or SEPT2-targeting shRNAs. Images were acquired by time-lapse TIRF microscopy (DeltaVision OMX V4; GE Healthcare) every 20 s for 15 min. Time display, minutes:seconds. Bars, 5 µm.

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

Lee Dolat, John L. Hunyara, Jonathan R. Bowen, Eva Pauline Karasmanis, Maha Elgawly, Vitold E. Galkin, and Elias T. Spiliotis

DOI: 10.1083/jcb.201405050