Video 2.

Detailed view of RGD and metal ions during headpiece opening. Ligand-interacting residues in αIIb are shown in sticks. The β3 subunit is shown as a wormlike trace with metal coordinating residues and Trp-129 in stick. Metal ions and water are shown as spheres. The color scheme is as for Video 1 except metals at SyMBS and ADMIDAS are shown in yellow, and the one at MIDAS is shown in cyan.


Complete integrin headpiece opening in eight steps

Jieqing Zhu, Jianghai Zhu, and Timothy A. Springer

DOI: 10.1083/jcb.201212037
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