Video 7.

Migration of CD4+ T-blasts and PMNs in rat tail collagen at low and high concentrations indicated in the movie in the presence of MMP-inhibitor GM6001. Imaged at 37°C by bright-field inverse microscopy (Leica); time (h:min:s) as indicated (2-min frame interval; 2 h of observation).


Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

Katarina Wolf, Mariska te Lindert, Marina Krause, Stephanie Alexander, Joost te Riet, Amanda L. Willis, Robert M. Hoffman, Carl G. Figdor, Stephen J. Weiss, and Peter Friedl

DOI: 10.1083/jcb.201210152
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