Live imaging of the mouse zygote during the first division. Mouse zygote expressing EGFP-MAP4 (microtubule; gray) and H2B-mRFP1 (DNA; cyan) during the first division. Images were analyzed by time-lapse confocal microscopy using a laser-scanning confocal microscope (LSM 780). Frames were taken every 2 min for 5 h and 40 min. See also Fig. 1 J. Time is given in hours and minutes relative to NEBD (at 00:00).