Video 2.

3D density map of GMPCPP microtubule with fitted atomic models of tubulins seen from the minus end of the microtubule.2.5-Å-thick clipping planes move parallel to the microtubule axis from the minus end of α-tubulin to the plus end of β-tubulin and then return to the minus end of α-tubulin. α-tubulin is colored red (N domain), cyan (I domain), and magenta (C domain), whereas β-tubulin is colored brown (N domain), blue (I domain), and purple (C domain).


Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

Hiroaki Yajima, Toshihiko Ogura, Ryo Nitta, Yasushi Okada, Chikara Sato, and Nobutaka Hirokawa

DOI: 10.1083/jcb.201201161
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