Apical extrusion of a dying cell from the epidermis of a 4-d-old zebrafish. The dying cell extrudes apically out of the epidermis and is trapped between fish and cover glass when zebrafish 4-d-old larvae are treated with 450 µg/ml G-418 and 0.2% DMSO (as carrier control). Frames were taken every 60 s using a 40× 0.8 W Nikon water immersion DIC lens.