Video 2.

Increased actin polymerization occurs as an early event during invadopodium maturation. A 10-min time-lapse video of a GFP-actin MTLn3 cell stimulated with EGF showing that barbed ends at invadopodium precursors peak between 1 and 2 min after stimulation with EGF. (green = GFP-actin). Images were acquired every 10 s and movie speed is 7 frames/second.


Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

Matthew Oser, Hideki Yamaguchi, Christopher C. Mader, J.J. Bravo-Cordero, Marianela Arias, Xiaoming Chen, Vera DesMarais, Jacco van Rheenen, Anthony J. Koleske, and John Condeelis

DOI: 10.1083/jcb.200812176
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