Video 4.

α-Tubulin localization and spindle dynamics through mitosis in wild-type cells. U2OS cells containing α-tubulin–mCherry were treated with control siRNA, filmed at 3-min intervals, and are displayed at 12 frames per second. Stills are shown in Fig. 6 b.

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

Alexander W. Bird , and Anthony A. Hyman

DOI: 10.1083/jcb.200802005