Video 3.

Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell undergoing cycles of metaphase chromosome decondensation and recondensation. The green fluorescent channel represents the endogenously expressed histone H2B fused to the GFP protein. The video sample rate is 1 frame for every 3 min of real time and the display rate is 2 frames per second. Bar, 16 μm.


Loss of ATRX leads to chromosome cohesion and congression defects

Kieran Ritchie , Claudia Seah , Jana Moulin , Christian Isaac , Frederick Dick , and Nathalie G. Bérubé

DOI: 10.1083/jcb.200706083
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