Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell undergoing cycles of metaphase chromosome decondensation and recondensation. The green fluorescent channel represents the endogenously expressed histone H2B fused to the GFP protein. The video sample rate is 1 frame for every 3 min of real time and the display rate is 2 frames per second. Bar, 16 μm.