Video 3.

Spontaneous symmetry breaking and motility initiation of keratocytes. Phase-contrast time-lapse video of a keratocyte spontaneously breaking symmetry and initiating motility. The cell has been reoriented such that the eventual direction of movement is to the right. 50x real time (frames were collected at 5-s intervals and are displayed at 10 frames/s). Corresponds to Fig. 2 A (cell A).


Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

Patricia T. Yam , Cyrus A. Wilson , Lin Ji , Benedict Hebert , Erin L. Barnhart , Natalie A. Dye , Paul W. Wiseman , Gaudenz Danuser , and Julie A. Theriot

DOI: 10.1083/jcb.200706012
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