Video 2.

ATP induces contraction of Mf cytoskeletons. Cytoskeletons were produced by extracting Mfs after a 7-d culture with TX-100. The addition of 100 mM ATP at the beginning of the sequence induces cytoskeleton contraction. Frames were recorded every 30 s for 23 min and the frame width is 250 μm.


Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix

Pierre-Jean Wipff , Daniel B. Rifkin , Jean-Jacques Meister , and Boris Hinz

DOI: 10.1083/jcb.200704042
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