Video 1.

Bub3^+/-/Rae1^+/- MEF undergoing a normal mitotic division. Mitosis was filmed from metaphase to late telophase. Frames were collected at 2-min intervals. The display rate is 1 frame/s. Chromosomes are visualized by ectopic expression of YFP-H2B (green).

Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice

Darren J. Baker , Karthik B. Jeganathan , Liviu Malureanu , Carmen Perez-Terzic , Andre Terzic , and Jan M.A. van Deursen

DOI: 10.1083/jcb.200507081