Video 3.

Dynamic movements of pDest-tdTomato-LC3 (red) and GFP-p62 (green). The fluorescent tagged constructs were transiently coexpressed in HeLa cells. One confocal plane was imaged for 3 min with a time interval of 4 s. The video is displayed as 10 frames per second.


p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy , Trond Lamark , Andreas Brech , Heidi Outzen , Maria Perander , Aud Øvervatn , Harald Stenmark , and Terje Johansen

DOI: 10.1083/jcb.200507002
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