Disease progression in 120-d-old Loa/SOD1G93A mice. This is an example of a Loa/SOD1G93A littermate of the mouse seen in Video 1, also at 120 d of age. This animal is much more active and moves freely around the bench. Furthermore, when suspended by the tail this animal displays the characteristic "Legs at odd angles" (Loa) reflex, and the hindlimbs are pulled in at an unusual angle.
