Video 7.

Another example of splaying of kinetochore fibers upon centrosome detachment in dynein-depleted cells. In this cell the spindle formed between the separated centrosomes, and the poles were initially well focused. However, at later time, the centrosomes detach from the poles and the kinetochore fibers splay so that the spindle becomes barrel shaped.


Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

Helder Maiato , Conly L. Rieder , and Alexey Khodjakov

DOI: 10.1083/jcb.200407090
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