Video 2.

Corresponds to images presented in Fig. 1 B. An example of spindle formation in a cell with centrosomes only partially separated by NEB. Note that kinetochore fibers that appear in association with those kinetochores that are oriented away from the centrosomes. These K-fibers converge and form an ectopic pole. However, over time, all distal K-fibers become incorporated into the main spindle that forms between the centrosomes.


Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

Helder Maiato , Conly L. Rieder , and Alexey Khodjakov

DOI: 10.1083/jcb.200407090
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