Video 1.

The video showsthe chromosomal localizationanddynamic redistributionof either topo IIα-GFP (top) or topo IIß-GFP (bottom) intwo cells(monitoredby transmittedlight[left] andby a single optical sectionof greenfluorescence [right]) asthey proceedthrough mitosisfrom prophase until early G1-phase.


Dynamics of human DNA topoisomerases IIα and IIβ in living cells

Morten O. Christensen , Morten K. Larsen , Hans Ullrich Barthelmes , Robert Hock , Claus L. Andersen , Eigil Kjeldsen , Birgitta R. Knudsen , Ole Westergaard , Fritz Boege , and Christian Mielke

DOI: 10.1083/jcb.200112023
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