Video 1.

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine

Giorgio Scita , Pierluigi Tenca , Liliana B. Areces , Arianna Tocchetti , Emanuela Frittoli , Giuseppina Giardina , Isabella Ponzanelli , Patrizia Sini , Metello Innocenti , and Pier Paolo Di Fiore

DOI: 10.1083/jcb.200103146