Video 8.

Platelets and neutrophils forming a thrombus in the IVC. Intravital time-lapse movie of a cross section of the IVC vessel wall (red) imaged by two-photon microscopy in LysM-eGFP mice (video still in Fig. 7 C). A developing thrombus (arrowhead) consisting of neutrophils (green) and platelets (yellow) is forming 4 h after DVT induction. Plasma is colored in blue (acquisition rate: 30 frames/min; frame rate: 8.04 frames/s).

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Marie-Luise von Brühl, Konstantin Stark, Alexander Steinhart, Sue Chandraratne, Ildiko Konrad, Michael Lorenz, Alexander Khandoga, Anca Tirniceriu, Raffaele Coletti, Maria Köllnberger, Robert A. Byrne, Iina Laitinen, Axel Walch, Alexander Brill, Susanne Pfeiler, Davit Manukyan, Siegmund Braun, Philipp Lange, Julia Riegger, Jerry Ware, Annekathrin Eckart, Selgai Haidari, Martina Rudelius, Christian Schulz, Katrin Echtler, Volker Brinkmann, Markus Schwaiger, Klaus T. Preissner, Denisa D. Wagner, Nigel Mackman, Bernd Engelmann, and Steffen Massberg

DOI: 10.1084/jem.20112322