Video 1.

Simulation of cGMP diffusion along the sperm flagellum. Diffusion of cGMP from a point source along the flagellum was calculated by using Eqs. 5–8 (Materials and methods). The concentration of cGMP is depicted in false colors. max conc, maximum concentration.

High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

Magdalena Pichlo, Stefanie Bungert-Plümke, Ingo Weyand, Reinhard Seifert, Wolfgang Bönigk, Timo Strünker, Nachiket Dilip Kashikar, Normann Goodwin, Astrid Müller, Heinz G. Körschen, Ursel Collienne, Patric Pelzer, Qui Van, Jörg Enderlein, Clementine Klemm, Eberhard Krause, Christian Trötschel, Ansgar Poetsch, Elisabeth Kremmer, and U. Benjamin Kaupp

DOI: 10.1083/jcb.201402027